Topic automatically created for discussing the designs at:
https://covid.postera.ai/covid/submissions/EDJ-MED-40433386
Interesting compounds. Do you anticipate a NH-OC intramolecular H-bond? (If made, you’;d see this in DMSO d6 1H NMR)… Possibility of a cyclised form e.g. a 5 membered NO heterocycle, oxetane or a saturated isoxazole type system to take out a HBD?