@mc-robinson will give a more detailed answer, what I can say quickly:
2. see this topic:
It is not so much what is potentially available as to what Enamine can actually make, in 2 weeks, from available building blocks. So there are further constraints.
3. Yes interested in both. Our current bet is that we have a better chance in gaining potency by focusing on covalent compounds for the “fast-track”. However we are using as many tools as we can to evaluate the quality of the designed compounds as possible, it is not straightforward. All the compounds designed are taken into account for the standard route.
4. Yes of course, the aim is to be an open data platform. The core team is working hard on trying to find the shortest way to impact, but the data is available for everybody to use, now or later.