Super, sure. Aldehyde oxidase is another one that’s poorly dealt with. We’ve been using the Baran Litmus test and it works a treat (CHF2 substitution correlates with AO susceptibility). Are triazoles A.O. substrates? Obviously to bear in mind @ a later stage.
BTW, latest J Med Chem is very useful I’m sure; it;'s on drug tox and lead optmisation strategies;
June 25, 2020 Volume 63, Issue 12
Pages 6249 - 6574
DOI: 10.1021/acs.jmedchem.9b00917.