BREED: finding merging opportunities

BREED: Generating Novel Inhibitors through Hybridization of Known Ligands:
https://pubs.acs.org/doi/10.1021/jm030543u

Although I can’t find the algorithm. Maybe it’s been incorporated into some commercial software.

Seems very similar to Fragmenstein.

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Hi yes it’s implemented in Maestro (part of the Schrodinger suite)
Can be OK for inspiration although I have to say that the results I’ve seen from Fragmentstein look better

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