miko_a

What is purpose of single fluorine atoms in some of these compounds, is it intended as NMR probe? Because if these are intended to go into a living organism, I’m afraid that some of these compounds (3, 4, 5, 15, 16, 17, 37, 58, 59, 65, 102, maybe 24, 35, 74, 75, 78, 94, 95, 99, 108, possibly others) could form (toxic) fluoroacetate during oxidative degradation. I see the same problem in ED_-GRI-5b13fbe2 in compounds 40, 41, 42, 43, 47